Open the folder and double-click the InDesign.exe file.

This is a completely free, open-source layout program.

If you absolutely must run it, do so in an offline VM. Then start migrating your workflow to modern, legal portable alternatives. Your future self (and your portfolio) will thank you.

Instead of making InDesign portable, make your entire Windows portable.

: Support for creating interactive PDFs and exporting to EPUB3 with layout enhancements for mobile devices.

Modern macOS versions (Catalina and later) completely dropped support for 32-bit applications and strict Gatekeeper protocols, making it virtually impossible to run old portable architecture on modern Apple hardware. 5. Legal and Ethical Ramifications

Scribus is a free, open-source DTP tool that does have an official portable version on .

Here is a look at what the genuine InDesign CS6 offered, compared to what you can get today: